|
The Journal of Bone and Joint Surgery, Vol 74, Issue 2 186-200, Copyright © 1992 by Journal of Bone and Joint Surgery, Inc
Prevention of heterotopic ossification with irradiation after total hip arthroplasty. Radiation therapy with a single dose of eight hundred centigray administered to a limited field
VD Pellegrini, AA Konski, JA Gastel, P Rubin and CM Evarts
University of Rochester School of Medicine and Dentistry, New York 14642.
Sixty-two hips in fifty-five patients who were considered to be at risk for
postoperative heterotopic ossification were randomly divided into two
groups: one received a single 800-centigray dose of limited-field radiation
and the other, 1000 centigray of limited-field radiation in divided doses.
The risk for heterotopic-bone formation was identified on the basis of
previously described criteria, which included previous heterotopic
ossification after an operation about the hip, hypertrophic osteoarthritis
or post-traumatic osteoarthrosis characterized by formation of extensive
osteophytes, radiographic evidence of diffuse idiopathic skeletal
hyperostosis, ankylosing spondylitis, and male sex. The treatment portals
excluded prosthetic surfaces that were intended for biological fixation by
ingrowth of bone. At a minimum six-month follow-up, progression of
heterotopic ossification had occurred in seven (21 per cent) of thirty-four
hips in the first group and in six (21 per cent) of twenty-eight hips in
the second group. The ossification had advanced more than one grade in only
one hip. Extra-field ossification occurred in fifteen (43 per cent) of
thirty-five hips that had not had previous heterotopic ossification. Since
the time of the study, the treatment portal has been modified to include
the lateral aspect of the greater trochanter, so that the risk of bursitis
associated with ossification in this area is minimized. Single-dose
limited-field radiation is effective for the prevention of heterotopic
ossification, without compromise of early fixation of an uncemented
implant.
 CiteULike  Connotea  Del.icio.us  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
B. K. Potter, T. C. Burns, A. P. Lacap, R. R. Granville, and D. A. Gajewski
Heterotopic Ossification Following Traumatic and Combat-Related Amputations. Prevalence, Risk Factors, and Preliminary Results of Excision
J. Bone Joint Surg. Am.,
March 1, 2007;
89(3):
476 - 486.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. R. Lynch, M. V. Jenkins, D. G. Smith, and C. Bellabarba
Bilateral Exercise-Induced Compartment Syndrome of the Thigh and Leg Associated with Massive Heterotopic Ossification. A Case Report
J. Bone Joint Surg. Am.,
October 1, 2006;
88(10):
2265 - 2269.
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. K. Potter, T. C. Burns, A. P. Lacap, R. R. Granville, and D. Gajewski
Heterotopic Ossification in the Residual Limbs of Traumatic and Combat-Related Amputees
J. Am. Acad. Ortho. Surg.,
September 1, 2006;
14(10):
S191 - S197.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Y. Carlier, D. M. L. Safa, P. Parva, D. Mompoint, T. Judet, P. Denormandie, C. A. Vallee, T. Judet, and P. Denormandie
Ankylosing neurogenic myositis ossificans of the hip: AN ENHANCED VOLUMETRIC CT STUDY
J Bone Joint Surg Br,
March 1, 2005;
87-B(3):
301 - 305.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. N. Rumi, G. S. Deol, J. A. Bergandi, K. P. Singapuri, and V. D. Pellegrini Jr.
Optimal Timing of Preoperative Radiation for Prophylaxis Against Heterotopic Ossification. A Rabbit Hip Model
J. Bone Joint Surg. Am.,
February 1, 2005;
87(2):
366 - 373.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Hebela, D. G. Smith, and M. A. Keenan
What's New in Orthopaedic Rehabilitation
J. Bone Joint Surg. Am.,
November 1, 2004;
86(11):
2577 - 2581.
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Iorio and W. L. Healy
Heterotopic Ossification After Hip and Knee Arthroplasty: Risk Factors, Prevention, and Treatment
J. Am. Acad. Ortho. Surg.,
November 1, 2002;
10(6):
409 - 416.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P G S Cornes, M Shahidi, and J P Glees
Heterotopic bone formation: irradiation of high risk patients
Br. J. Radiol.,
May 31, 2002;
75(893):
448 - 452.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. A. Burd, K. J. Lowry, and J. O. Anglen
Indomethacin Compared with Localized Irradiation for the Prevention of Heterotopic Ossification Following Surgical Treatment of Acetabular Fractures
J. Bone Joint Surg. Am.,
December 1, 2001;
83(12):
1783 - 1788.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T C M Lo and W L Healy
Re-irradiation for prophylaxis of heterotopic ossification after hip surgery
Br. J. Radiol.,
June 1, 2001;
74(882):
503 - 506.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. D. PELLEGRINI JR. and S. J. GREGORITCH
Preoperative Irradiation for Prevention of Heterotopic Ossification following Total Hip Arthroplasty
J. Bone Joint Surg. Am.,
June 1, 1996;
78(6):
870 - 81.
[Abstract]
[Full Text]
|
|
|
|
