The Journal of Bone and Joint Surgery, Vol 73, Issue 9 1376-1381, Copyright © 1991 by Journal of Bone and Joint Surgery, Inc
Paget disease of the spine
A Hadjipavlou and P Lander
Paget's and Osteoporosis Clinic, McGill University, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.
Seventy patients who had the radiographic features of Paget disease of the
spine were evaluated clinically and with computed tomography, with the
objective of correlation of the symptoms with the lesions. Of forty-five
symptomatic patients, twenty-one had only pain in the back or neck and
twenty-four patients had spinal stenosis with or without pain in the back
or neck. Seven patients had a neurological deficit without pain, nineteen
had so-called mechanical or arthritic pain, nine had pain that was
attributable to the Paget lesion, and ten had a combination of the two
types of pain. The most common cause of the spinal stenosis was expansion
of bone that led to compression of the thecal sac and its neural elements.
In one patient, the cord was compromised further by a pathological fracture
of the eighth thoracic vertebra. There was a strong correlation between the
presence of symptoms and the findings of spinal stenosis and arthropathy of
the facets (zygapophyseal joints) on computed tomography. The spinal
stenosis and the arthropathy of the facets were caused by the abnormal,
hyperactive bone-remodeling, which resulted in the expansion of the osseous
elements of the involved vertebra or vertebrae.