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The Journal of Bone and Joint Surgery, Vol 72, Issue 6 878-883, Copyright © 1990 by Journal of Bone and Joint Surgery, Inc
Infection as a complication of total knee-replacement arthroplasty. Risk factors and treatment in sixty-seven cases
MG Wilson, K Kelley and TS Thornhill
Brigham and Women's Hospital, Boston, Massachusetts 02115.
Of 4171 total knee arthroplasties that were performed at our institution
from 1973 to 1987, sixty-seven were followed by infection. The risk of
infection was significantly increased in patients, particularly men, who
had rheumatoid arthritis; in patients who had ulcers of the skin; and in
patients who had had a previous operation on the knee. Infection was also
associated with obesity, recurrent urinary-tract infection, and oral use of
steroids, although the correlation was not statistically significant. Of
the various treatment options that were studied, removal and delayed
replacement of the knee prosthesis resulted in the best functional results.

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