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The Journal of Bone and Joint Surgery, Vol 71, Issue 9 1363-1370, Copyright © 1989 by Journal of Bone and Joint Surgery, Inc
Experimental models to promote healing of tears in the avascular segment of canine knee menisci
DH Gershuni, MJ Skyhar, LA Danzig, J Camp, AR Hargens and WH Akeson
Division of Orthopaedics and Rehabilitation, Veterans Administration Medical Center, San Diego, California 92161.
Longitudinal tears were created in canine lateral menisci and techniques
were applied to induce healing by removal of a core of tissue from the
periphery of the meniscus to the tear or by implantation of a vascularized
synovial flap into the tear. The meniscal tears did not heal in knees that
were not immobilized, and they healed poorly and sporadically in knees that
were immobilized in a cast but bore some weight. However, a higher
percentage of tears that were treated by the core-removal or synovial-flap
technique healed when the knee was firmly immobilized and weight-bearing
was prevented by the use of an external skeletal fixator across the joint
for eight to twelve weeks. Neovascularization and access to a source of
reparative cells appear to be important in the healing process.

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