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The Journal of Bone and Joint Surgery, Vol 71, Issue 1 105-112, Copyright © 1989 by Journal of Bone and Joint Surgery, Inc

JOURNAL CONTENTS

Chronic recurrent multifocal osteomyelitis. Association with vertebra plana

L Yu, JR Kasser, E O'Rourke and H Kozakewich
Department of Orthopaedic Surgery, Children's Hospital, Boston, Massachusetts 02115.

In seven children who had chronic recurrent multifocal osteomyelitis, the radiographic and histological findings were consistent with those of osteomyelitis, but the results of cultures were negative. We studied the clinical, radiographic, histological, and microbiological findings in these patients, who had a total of thirty-nine lesions. The lesions occurred most frequently in the spine, tibia, and femur; three patients had vertebra plana. The natural history of chronic recurrent multifocal osteomyelitis appears to be slow, spontaneous resolution of the osseous lesions without specific treatment. The diagnosis is one of exclusion. Biopsy is recommended, and results of cultures must be negative before therapy with antibiotics can be withheld.
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