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The Journal of Bone and Joint Surgery, Vol 70, Issue 8 1124-1130, Copyright © 1988 by Journal of Bone and Joint Surgery, Inc

JOURNAL CONTENTS

Surgical treatment for osteosarcoma

DS Springfield, R Schmidt, J Graham-Pole, RB Marcus, SS Spanier and WF Enneking
Department of Orthopaedics, University of Florida, Gainesville 32610.

Fifty-three patients who had a high-grade osteosarcoma had either a limb-salvage resection or an amputation. They all received adjuvant therapy that consisted of administration of Adriamycin (doxorubicin) and whole-lung irradiation. At the time of follow-up, the surgical margin was assessed by examination of the surgical specimen. Each patient was followed for at least three years or until death. The data suggested that a wide surgical margin is adequate to control a primary osteosarcoma. When a wide surgical margin can be used and a functional limb can be salvaged, an amputation probably is not required.
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