The Journal of Bone and Joint Surgery, Vol 70, Issue 1 70-75, Copyright © 1988 by Journal of Bone and Joint Surgery, Inc
Replantation of an autoclaved autogenous segment of bone for treatment of chondrosarcoma. Long-term follow up
WS Smith and S Struhl
Section of Orthopaedic Surgery, University of Michigan Hospital, Ann Arbor 48109.
Seven patients who had a low-grade chondrosarcoma of the proximal part of
the humerus or femur were treated by resection, autoclaving of the excised
segment, and reinsertion of that segment with supplementary fresh
autogenous grafts. The length of follow-up ranged from fourteen to
twenty-four years, and sequential roentgenograms were made during the
follow-up period. A biopsy of the autoclaved segments was done in one
patient eleven years after the operation, and examination of the specimen
showed predominantly live bone; there were very few spicules of dead bone.
Although the principal roentgenographic changes were demonstrated by the
end of the first year, serial roentgenograms showed a continuing process of
remodeling for two decades. No secondary procedures were required for
treatment of fracture, resorption, infection, or loss of function.