The Journal of Bone and Joint Surgery, Vol 68, Issue 8 1225-1230, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc
Benign fibrous histiocytoma of bone
F Bertoni, P Calderoni, P Bacchini, A Sudanese, N Baldini, D Present and M Campanacci
The cases of seven patients who had a lytic lesion that was histologically
similar to a metaphyseal fibrous defect (non-ossifying fibroma) of bone
were studied. The patients all were adults and had pain without a fracture.
These features were considered distinctive for the lesion, which has the
same histological appearance as benign fibrous histiocytoma of soft tissue.
The lesion is a benign tumor with fibroblastic and histiocytic
differentiation. This picture may be seen in foci in other lesions of bone
(aneurysmal bone cyst, fibrous dysplasia, and giant-cell tumor). Ten cases
of giant-cell tumor of bone that had a large component of the same foci
were also reviewed. It should be emphasized that these areas are secondary
reactive tissue rather than the true neoplastic tissue of benign fibrous
histiocytoma.