The Journal of Bone and Joint Surgery, Vol 68, Issue 8 1210-1217, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc
Chronic non-hematogenous osteomyelitis treated with adjuvant hyperbaric oxygen
JC Davis, JD Heckman, JC DeLee and FJ Buckwold
Between 1979 and 1982, thirty-eight patients with chronic non-hematogenous
osteomyelitis were treated by local debridements of the wound, prolonged
parenteral administration of antibiotics, and an average of forty-eight
once-a-day treatments with hyperbaric oxygen. Of these thirty-eight
patients, thirty-four remained free of clinical signs of osteomyelitis for
an average of thirty-four months (range, twenty-four to fifty-nine months)
after this regimen of treatment. Only four of the thirty-eight patients had
been free of clinical signs of osteomyelitis for as long as three months
during the two years preceding this treatment. Three of the four failures
of treatment were evident within one month after treatment. This method of
treatment appears to prolong the infection-free interval of patients with
chronic non-hematogenous osteomyelitis.
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