The Journal of Bone and Joint Surgery, Vol 68, Issue 7 1057-1061, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc
Chronic arthritis of the knee in Lyme disease. Review of the literature and report of two cases treated by synovectomy
TP McLaughlin, L Zemel, RL Fisher and HR Gossling
The arthritis that may be a part of Lyme disease, a spirochetal infection
transmitted by ticks, has not been widely reported in the orthopaedic
literature. Established chronic arthritis in patients who have Lyme disease
most commonly affects the knee and may cause erosive joint disease.
Antibiotics given early in the course of the disease can prevent chronic
arthritis. When the arthritis is established, penicillin administered
intravenously is curative in as many as 55 per cent of patients, but
medical therapy alone may be insufficient to successfully treat the chronic
stage of arthritis.