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The Journal of Bone and Joint Surgery, Vol 68, Issue 5 747-751, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc

JOURNAL CONTENTS

Osteoid-osteoma: intraoperative tetracycline-fluorescence demonstration of the nidus

AG Ayala, JA Murray, MA Erling and AK Raymond

Nine patients with a clinical and radiographic diagnosis of osteoid-osteoma received 750 to 4,000 milligrams of tetracycline preoperatively. Immediate examination of the surgically removed specimens under ultraviolet light demonstrated fluorescence of the nidus in all nine patients. Reactive and normal bone did not fluoresce. This simple technique permits quick, easy, economical, and sure verification that the nidus has been excised.
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