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The Journal of Bone and Joint Surgery, Vol 68, Issue 3 376-385, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc
Replacement of the anterior cruciate ligament using a patellar tendon allograft. An experimental study
SP Arnoczky, RF Warren and MA Ashlock
The anterior cruciate ligament of twenty-five adult dogs was replaced using
fresh or deep-frozen patellar-tendon allografts. The morphology of these
transplanted allografts was then evaluated using routine histological
studies and a vascular-injection (Spalteholz) technique at various
intervals from two weeks to one year postoperatively. The fresh
patellar-tendon allografts incited a marked inflammatory and rejection
response which was characterized by perivascular cuffing and lymphocyte
invasion. Deep-frozen patellar-tendon allografts appeared to be benign
within the joint and underwent alterations that were comparable with those
observed in autogenous patellar-tendon grafts. These included avascular
necrosis followed by revascularization and cellular proliferation. At one
year, the gross and histological appearance of the patellar tendon
allograft resembled that of a normal anterior cruciate ligament.
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