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The Journal of Bone and Joint Surgery, Vol 68, Issue 2 235-242, Copyright © 1986 by Journal of Bone and Joint Surgery, Inc
Giant-cell tumor of bone
DJ McDonald, FH Sim, RA McLeod and DC Dahlin
Our experience involving 221 consecutive patients with giant-cell tumor who
were treated from 1960 to 1982 is reported. Of one group of 146 patients,
twenty-seven who were initially treated by wide resection and 112 who had
thorough curettage had a recurrence rate of 23 per cent after an average
length of follow-up of seven years. All thirty-three recurrences were noted
less than six years after operation, and twenty-seven were noted within the
first three years postoperatively. Over-all, the type of surgical removal
was the most significant factor in recurrence. The recurrence rate was 34
per cent in the patients who had curettage of the lesion and 7 per cent in
those who had a wide resection. In a second group of seventy-five patients,
initially treated by us for a recurrent tumor, there were fifteen
subsequent recurrences, after an average length of follow-up of seven
years. Curettage and bone-grafting, with preservation of function of the
joint, is the preferred treatment for most patients.
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