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The Journal of Bone and Joint Surgery, Vol 65, Issue 6 719-728, Copyright © 1983 by Journal of Bone and Joint Surgery, Inc

JOURNAL CONTENTS

Predicting the success of reambulation in patients with Duchenne muscular dystrophy

PJ Vignos, MB Wagner, JS Kaplan and GE Spencer

We used biochemical and clinical variables to develop a method to predict the expected duration of independent walking following surgery and bracing in patients with Duchenne muscular dystrophy. Data from the records of fifty patients were analyzed by linear and multiple regression. The most useful factors, applied in combination, in predicting the duration of walking ability after bracing were: percentage of residual muscle strength, vital capacity, creatinine coefficient, motivation of the patient at the time of bracing, and decrease in creatinine coefficient in the two years prior to bracing. This system uses readily available variables to predict the response to bracing in patients with Duchenne muscular dystrophy. Improvement in the criteria for the selection of patients for surgery and bracing is important in view of the economic cost as well as the demands on the time and energy of these children and their parents.
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