The Journal of Bone and Joint Surgery, Vol 64, Issue 5 755-761, Copyright © 1982 by Journal of Bone and Joint Surgery, Inc
Giant-cell tumor of bone: analysis of two hundred and eight cases in Chinese patients
HW Sung, DP Kuo, WP Shu, YB Chai, CC Liu and SM Li
Giant-cell tumor of bone seems to occur more frequently in Chinese people
than in those residing in Western countries. The estimated incidence is
about 20 per cent of all primary tumors of bone. Of 208 surgically treated
and pathologically proved giant-cell tumors, 194 were benign. We excluded
patients with primary or secondary amputation unrelated to recurrence and
those followed for less than two years or lost to follow-up. Of the
remaining 111 patients who were followed for more than two years,
twenty-nine had a recurrence, giving a recurrence rate of 26.1 per cent.
The rate of recurrence was highest following curettage and bone-grafting
(41.2 per cent) and was much lower in patients who were treated by
resection and fusion (7.1 per cent). Since resection of this tumor with
reconstructive procedures, either by massive homogenous bone-grafting or
artificial joint replacement, is complicated and might cripple the patient
if it fails, we propose excision and curettage with bone-grafting as the
most suitable method of treatment in the majority of patients with
giant-cell tumor of bone.
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