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The Journal of Bone and Joint Surgery, Vol 63, Issue 8 1248-1257, Copyright © 1981 by Journal of Bone and Joint Surgery, Inc
Chondrosarcoma of bone. The experience at the Istituto Ortopedico Rizzoli
S Gitelis, F Bertoni, P Picci and M Campanacci
We retrospectively reviewed the records of 125 patients with chondrosarcoma
seen at the Istituto Ortopedico Rizzoli. All of the patients had been
followed for at least five years, and ninety-six patients had been followed
for at least ten years. The requirements for the adequacy of treatment were
carefully defined. Metastasis and survival were related to the histological
grade of the tumor. Nine per cent of the grade-1 lesions and 44 per cent of
the grade-3 lesions metastasized. Ninety-four per cent of the patients with
grade-1 lesions survived for five years, compared with only 44 per cent of
patients with grade-3 lesions. The ten-year survival rates were 87 per cent
and 27 per cent, respectively. Adequacy of treatment had an important
influence on the incidence of recurrence, length of survival, and length of
disease-free survival. The incidence of recurrence in adequately treated
patients was 6 per cent, but in inadequately treated patients it was 69 per
cent. The five-year survival rates in these two groups were 81 per cent and
53 per cent, respectively. Seventy-eight per cent of the adequately treated
patients were disease-free at follow-up (mean, 11.1 years) compared with
only 6 per cent of the inadequately treated patients. We compared the
results of this review with those of other reviews of chondrosarcoma.

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