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The Journal of Bone and Joint Surgery, Vol 62, Issue 5 826-828, Copyright © 1980 by Journal of Bone and Joint Surgery, Inc

JOURNAL CONTENTS

The antimicrobial effectiveness of operative-site preparative agents: a microbiological and clinical study

MA Ritter, ML French, HE Eitzen and TJ Gioe

Eight wound preparative agents (one triclosan compound, one hexachlorophene compound, and six iodophors) were evaluated under actual operating-room conditions for efficacy in de-germing the operative site prior to the performance of 310 total hip arthroplasties. All of the preparations tested achieved a significant reduction (p less than or equal to 0.001) of indigenous skin microflora compared with the pre-scrub level in both the post-scrub and the postoperative cultures. Two iodophors, when applied as sprays, demonstrated excellent bactericidal action, were less time-consuming and easier to use than the compounds that were applied as scrubs, and did not alter the low (0.42 per cent) infection rate that we have recorded over a period of four years.
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Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Prevention of Deep Periprosthetic Joint Infection*{{dagger}}
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