The Journal of Bone and Joint Surgery, Vol 62, Issue 5 811-815, Copyright © 1980 by Journal of Bone and Joint Surgery, Inc
Myositis ossificans following forcible manipulation of the leg. A rabbit model for the study of heterotopic bone formation
JE Michelsson, G Granroth and LC Andersson
The right hind limbs of forty-four rabbits were immobilized with the knee
in extension for as long as five weeks, except for a daily session of
forcible mobilization lasting five minutes. Within five weeks there was
progressive heterotopic-bone formation in the quadriceps muscle. The
roentgenographic and histological changes were similar to those seen in
human myositis ossificans.