The Journal of Bone and Joint Surgery, Vol 61, Issue 2 207-215, Copyright © 1979 by Journal of Bone and Joint Surgery, Inc
Osteosarcoma with small cells simulating Ewing's tumor
FH Sim, KK Unni, JW Beabout and DC Dahlin
Twenty-four patients who had osseous lesions with histological features of
both Ewing's sarcoma and osteosarcoma were studied. Because of their
appearance, these lesions have been labeled small-cell osteosarcomas. They
appear to represent a definite histological entity and the prognosis may be
worse for these lesions than for conventional osteosarcomas. It is most
important not to misdiagnose this tumor as Ewing's sarcoma because it
appears not to be radiosensitive. Radical surgery and modern adjuvant
chemotherapy seem to offer the best chance of cure.