The Journal of Bone and Joint Surgery, Vol 60, Issue 8 1131-1135, Copyright © 1978 by Journal of Bone and Joint Surgery, Inc
Tumoral calcinosis. A clinical and pathological study of eleven unreported cases in Turkey
U Hacihanefioglu
Clinicopathological observations of eleven cases of tumoral calcinosis are
reported. All of the cases showed characteristic clinical and
histopathological features of this unusual condition, but pathological
findings did not elucidate all of its etiology and pathogenesis. Two of the
patients were related. One of the patients showed skeletal changes
characterized by diffuse calcium deposits with widespread soft-tissue
calcification. The available data of the present study also led to the
suggestion that the disease has a genetic background and that the primary
defect may well be in the collagen which undergoes calcification.