The Journal of Bone and Joint Surgery, Vol 60, Issue 7 925-929, Copyright © 1978 by Journal of Bone and Joint Surgery, Inc
The spine in osteogenesis imperfecta
DR Benson, DH Donaldson and EA Millar
A high incidence of spinal curvature, approaching 80 per cent in patients
more than twelve years old, was found in a large series of patients with
osteogenesis imperfecta. Curves showed early progression and a predictable
pattern. In the age range between one and five years the incidence of
scoliosis was 26 per cent; thereafter, it rose precipitously. The degree of
curvature was greater in the older children. The Milwaukee brace was
ineffective in the treatment of the scoliosis and the complications of its
use were detrimental. In several patients it deformed the rib cage. It had
little or no effect on the progression of the curve. The incidence and
degree of curvature was related to the type of bone present. Patients with
chest deformities and those who were not ambulatory seemed to have a
predilection for scoliosis.