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The Journal of Bone and Joint Surgery, Vol 59, Issue 8 1076-1081, Copyright © 1977 by Journal of Bone and Joint Surgery, Inc


JOURNAL CONTENTS

The ultrastructure of the growth plate in slipped capital femoral epiphysis

MR Mickelson, IV Ponseti, RR Cooper and JA Maynard

Core biopsy specimens of the proximal femoral growth plate from three patients with slipped capital femoral epiphysis were studied by light and electron microscopy. In the resting zone, the cartilage matrix was composed of large, densely packed collagen fibrils. The cartilage matrix in the zones of chondrocyte hypertrophy where the slippage occurred contained only scattered fine collagen fibrils in a homogeneous ground substance. The change in composition of cartilage matrix in the distal region of the epiphyseal plate may predispose that region to slippage.
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