The Journal of Bone and Joint Surgery, Vol 59, Issue 5 632-647, Copyright © 1977 by Journal of Bone and Joint Surgery, Inc
Juxtacortical (parosteal) osteogenic sarcoma: histological grading and prognosis
SC Ahuja, AB Villacin, J Smith, PG Bullough, AG Huvos and RC Marcove
In twenty-four cases of juxtacortical osteogenic sarcoma, three
histological grades of malignancy were identified and correlated with the
prognosis. The eighteen patients with Grade-I or II tumors had a
significantly better prognosis than the six with Grade-III lesions. The
three grades could not be distinguished roentgenographically. Grade I and
II tumors, which showed a high cure rate after amputation, may be amenable
to en block resection, provided the entire tumor can be removed with a good
margin of uninvolved soft tissue and underlying bone. Grade-III tumors, on
the other hand, had a poor prognosis despite early radical surgery.