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The Journal of Bone and Joint Surgery, Vol 59, Issue 5 622-624, Copyright © 1977 by Journal of Bone and Joint Surgery, Inc


JOURNAL CONTENTS

Metal carcinogenesis: a study of the carcinogenic activity of solid metal alloys in rats

A Gaechter, J Alroy, GB Andersson, J Galante, W Rostoker and F Schajowicz

The carcinogenic activity of seven metallic alloys was studied by implanting solid rods of each alloy in the gluteal muscles of Sprague-Dawley rats which were killed after twenty-four months. When the number of tumors in these rats was compared with the numbers in rats not operated on, in rats which had a sham operation, and in rats implanted with Silastic rods, no statistically significant differences in the incidences of the tumors in the several groups were found.
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