The Journal of Bone and Joint Surgery, Vol 59, Issue 3 376-385, Copyright © 1977 by Journal of Bone and Joint Surgery, Inc
The effect of fixation with intramedullary rods and plates on fracture-site blood flow and bone remodeling in dogs
SE Barron, RA Robb, WF Taylor and PJ Kelly
Of fifty-seven adult dogs in which standard bilateral mid-ulnar fractures
were produced, thirty-four had one side fixed with either a tight-fitting
intramedullary Steinmann pin or a four-hole plate while the other side was
not fixed, and twenty-three had a plate on one side and an intramedullary
rod on the other. The blood flow at the fracture site, as determined by
85Sr clearance, was significantly less on the rod-fixed side than on the
plate-fixed side at fourteen and ninety days, while the total ulnar blood
flow was significantly higher on the rod-fixed than on the platefixed side
at one and fourteen days but was the same on both sides thereafter. When
the plate-fixed and rod-fixed fracture sites in the same dog were compared
with respect to periosteal and endosteal bone formation as determined by
tetracycline labeling anc microradiography, bone formation, like the blood
flow, was greater in the callus of the ulnae fixed by plates. However, at
ninety days, when healing had advanced to a point when the extent of union
could be judged clinically, union had occurred in both ulnae of six of the
seven dogs with both types of fixation studied at this time and was delayed
in both ulnae of the remaining dog.