The Journal of Bone and Joint Surgery, Vol 58, Issue 4 509-516, Copyright © 1976 by Journal of Bone and Joint Surgery, Inc
The permeability of articular cartilage under compressive strain and at high pressures
JM Mansour and VC Mow
The permeability of bovine articular cartilage was measured in an apparatus
designed to permit this measurement while the fluid pressure gradient
across the cartilage and the axial compressive strain applied to the
cartilage were varied independently. For all of the pressure gradients
tested the permeability of the cartilage decreased as the compressive
strain increased. From previous work, it was postulated that joint
lubrication is accomplished first by fluid exudation into the joint space.
both at the leading edge of the moving contact area and between portions of
the opposing cartilaginous surfaces, and second by imbibition of the
expelled fluid back into the cartilage toward the trailing edge of the
contact area caused by the "elastic" recovery of the tissue. The present
work extends this model to include the condition that the permeability of
cartilage is dependent on the extent to which it is deformed.