The Journal of Bone and Joint Surgery, Vol 58, Issue 3 393-395, Copyright © 1976 by Journal of Bone and Joint Surgery, Inc
Lavage of septic joints in rabbits: effects of chondrolysis
D Daniel, W Akeson, D Amiel, M Ryder and J Boyer
Septic joints were produced in rabbits which were then treated with
systemic procaine penicillin. One group of animals also had surgical lavage
at four and seven days after bacterial inoculation. In the infected joints
there was a significant loss of hexosamine by five days and of collagen by
nine days. Lavage delayed the loss of collagen.