The Journal of Bone and Joint Surgery, Vol 57, Issue 3 368-377, Copyright © 1975 by Journal of Bone and Joint Surgery, Inc
Direct-current stimulation of non-union and congenital pseudarthrosis. Exploration of its clinical application
CT Brighton, ZB Friedenberg, LM Zemsky and PR Pollis
Based on the response of bone to electrical current in previous studies, an
exploratory clinical study of the effect of electrical current on non-union
and congenital pseudarthrosis was performed. Constant direct current of ten
to twenty microamperes was applied to twenty-four non-unions and five
congenital pseudarthroses. Complete union occurred in fifteen non-unions
and in one congenital pseudarthrosis. A single cathode delivering ten
microamperes seemed sufficient to heal non-union in small bones, but
multiple cathodes each delivering twenty microamperes appeared to be
required to heal non-union in the tibia and femur. As the technique was
refined, the percentage of successes increased. While these preliminary
results appear promising, further laboratory and clinical experiments are
required to define the true role of electrical stimulation in clinical
practice.