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Journal of Bone and Joint Surgery, 1974;56:932-940.
© 1974 by The Journal of Bone and Joint Surgery, Inc

Malignant Fibrous Histiocytoma and Osteosarcoma in Association with Bone Infarcts

REPORT OF FOUR CASES, TWO IN CAISSON WORKERS

JOSEPH M. MIRRA M.D.1, PETER G. BULLOUGH M.D.2, RALPH C. MARCOVE M.D.2, BERNARD JACOBS M.D.2, and ANDREW G. HUVOS M.D.3

1 Department of Pathology, Center for the Health Sciences, University of California, Los Angeles, California 90024
2 535 East 70th Street, New York, N.Y. 10021
3 444 East 68th Street, New York, N.Y. 10021

Four patients, two of them former caisson workers, had malignant tumors of bone associated with bone infarcts in the femur. One of the tumors was osteogenic sarcoma and the other three were malignant fibrous histiocytomas. Despite amputation and other treatment, only one patient survived.


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