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Journal of Bone and Joint Surgery, 1974;56:322-327.
© 1974 by The Journal of Bone and Joint Surgery, Inc


The Response of Transplanted Articular Cartilage to Growth Hormone

ISADORE G. YABLON M.D., F.R.C.S.(C)1, CARL FRANZBLAU PH.D.1, and ROBERT E. LEACH M.D.1

1 From the Department of Orthopaedic Surgery, University Hospital, Boston University Medical Center, Boston

The response of transplanted articular cartilage in dogs to a biological stimulus was studied by injecting the recipient of the homograft with growth hormone and observing the activity of H3-hydroxyproline and 35S. There was a tenfold increase in activity of H3-hydroxyproline and 35S in those animals which received growth hormone.


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