Journal of Bone and Joint Surgery, 1973;55:69-77.
© 1973 by The Journal of Bone and Joint Surgery, Inc
Purpura Fulminans
JAMES R. URBANIAK M.D.1,
MICHAEL T. O'NEIL M.D.1, and
LESLIE C. MEYER M.D.1
1 From the Division of Orthopaedic Surgery, Duke University Medical Center, Durham, and Shriners Hospital for Crippled Children, Greenville
Six patients, aged four months to six years, had purpura fulminans following various types of febrile illness. Gangrenous involvement of varying degree and location required either amputation or multiple operative procedures, such as skin grafts, fascial releases, and osteotomies. Early treatment for shock and then heparinization to minimize thrombosis will prevent much orthopaedic intravascular disability, but early splinting and nursing care are also helpful.