Journal of Bone and Joint Surgery, 1972;54:1070-1072.
© 1972 by The Journal of Bone and Joint Surgery, Inc
Perforation of Colonic Diverticula
A LIFE-THREATENING POSTOPERATIVE COMPLICATION IN PATIENTS RECEIVING LONG-TERM C0RTIC0STER0ID THERAPY
THOMAS S. RENSHAW M.D.1 and
DENNIS B. PHELPS M.D.1
1 From the Section of Orthopaedic Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor
A potentially fatal postsurgical complication which may occur in patients who have had long-term steroid therapy is the perforation of colonic diverticula in the early postoperative period.
Three cases of this complication are reported, and the pertinent literature is reviewed. The presence of diverticulosis in patients who have had long-term steroid administration may increase the risk of any proposed surgical procedure. Postoperative abdominal symptoms in these patients are cause for immediate concern. Their inflammatory responses are altered and they may not exhibit the characteristic changes in temperature and laboratory studies typical of peritonitis.