Journal of Bone and Joint Surgery, 1972;54:874-877.
© 1972 by The Journal of Bone and Joint Surgery, Inc
Sporotrichosis Arthritis and Tenosynovitis
REPORT OF A CASE CURED BY SYNOVECTOMY AND AMPHOTERICIN B
KENNETH E. DEHAVEN M.D.1,
ALAN H. WILDE M.D.1, and
JOHN D. O'DUFFY M.D.1
1 From the Departments of Orthopaedic Surgery and Rheumatic Disease, The Cleveland Clinic Foundation, Cleveland
A case of extracutaneous sporotrichosis causing arthritis of a metacarpophalangeal joint of the hand, and tenosynovitis of the extensor carpi ulnaris has been reported. Iodide therapy, as is frequently the case, was not successful and the toxicity of amphotericin B precluded the administration of a curative dose. However, the combination of synovectomy and amphotericin-B therapy was effective, with no evidence of residual infection three years after the completion of treatment.