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Journal of Bone and Joint Surgery, 1972;54:181-188.
© 1972 by The Journal of Bone and Joint Surgery, Inc

A Case of Adult-Onset Vitamin-D Resistant Osteomalacia with Elevated Plasma Parathyroid Hormone Level

TAKUO FUJITA M.D.1, KAZUTOSHI OKANO M.D.1, HAJIME ORIMO M.D.1, MASAHIRO OHATA M.D.1, and MASAKI YOSHIKAWA M.D.1

1 From the Department of Geriatrics, University of Tokyo, Tokyo

A sixteen-year-old girl with adult-onset vitamin-D resistant osteomalacia had an elevated plasma immunoreactive parathyroid hormone level which was readily suppressed by intravenous calcium infusion. Treatment with 300,000 units of vitamin D2 normalized the high plasma immunoreactive parathyroid hormone level as well as augmented phosphaturia. Parathyroid hormone appears to play an important role in the development of vitamin-D resistant rickets in this case.


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