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Journal of Bone and Joint Surgery, 1971;53:1541-1550.
© 1971 by The Journal of Bone and Joint Surgery, Inc

Orthopaedic Defects in Familial Dysautonomia

A REVIEW OF SIXTY-FIVE CASES

WILFRED YOSLOW M.D.1, MELVIN H. BECKER M.D.1, JOHANNES BARTELS M.D.1, and WALTER A. L. THOMPSON M.D.1

1 From the Departments of Orthopedic Surgery, Radiology, and Anesthesiology, New York University Medical Center, New York

Familial dysautonomia is a rare autosomal disorder of the central nervous system characterized by many abnormalities, several of which are important to the orthopaedic surgeon. Sixty-five patients, thirty-seven girls and twenty-eight boys, with this disease were evaluated orthopaedically either by direct contact, questionnaire, or examination of records. The patients ranged in age from nine months to twenty-nine years. The orthopaedic features specifically studied were scoliosis (thirty-nine patients), fractures (nineteen patients), and osteochondritis, in varying sites, in six patients.


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