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Journal of Bone and Joint Surgery, 1971;53:1271-1280.
© 1971 by The Journal of Bone and Joint Surgery, Inc

Prevention of Thromboembolic Disease after Elective Surgery of the Hip

CHARLES M. EVARTS M.D.1 and EDWARD J. FEIL M.D.1

1 From the Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland

1. A high incidence (53.6 per cent) of venous thrombosis occurs after elective surgery of the hip.

2. The diagnosis of venous thrombosis by clinical signs and symptoms is far less sensitive than by venography.

3. Low molecular weight dextran has a marked protective effect against the occurrence of thromboembolism as demonstrated in a controlled study of 106 elective hip operations.

4. Low molecular weight dextran has been shown to be safe as well as effective.

5. The prophylactic administration of low molecular weight dextran is recommended for patients undergoing elective surgery of the hip.


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