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Journal of Bone and Joint Surgery, 1969;51:1369-1375.
© 1969 by The Journal of Bone and Joint Surgery, Inc


Destructive Lesions of the Spine in Rheumatoid Ankylosing Spondylitis

DONALD G. KANEFIELD M.D.1, B. P. MULLINS M.D.1, ALVIN A. FREEHAFER M.D.1, J. GEORGE FUREY M.D.1, SIMON HORENSTEIN M.D.1, and WILLIAM B. CHAMBERLIN M.D.1

1 From the Orthopaedic Surgery, Neurology, and Pathology Services of Highland View Hospital, Case Western Reserve University School of Medicine, Cleveland

Three patients with ankylosing spondylitis complicated by destructive vertebral lesions have been reported. One patient had three separate lesions over a ten-year period. Another patient sustained a fracture through the posterior elements prior to the occurrence of granuloma formation of the intervertebral space. The third patient had spinal-cord compression with complete paralysis from which he had a partial recovery following recumbency, lateral rachitomy, and fusion.

The etiology of these lesions is unknown, but it is suggested that they represent response to delayed union or non-union of fractures occurring in rheumatoid spondylitis.


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