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Journal of Bone and Joint Surgery, 1969;51:1360-1368.
© 1969 by The Journal of Bone and Joint Surgery, Inc

Reconstitution of Vertebral Height in Histiocytosis X: A Long-Term Follow-up

MARK E. NESBIT M.D.1, STEPHEN KIEFFER M.D.1, and G. J. D'ANGIO M.D.1

1 From the Departments of Pediatrics and Radiology, University of Minnesota Medical Center, Minneapolis

Ten children with histiocytosis X with vertebral column involvement were followed through the natural course of the disease. The characteristic roentgen findings were (1) a variable degree of collapse of a vertebral body, (2) no thinning or thickening of the adjacent intervetebral discs, and (3) absence of a soft-tissue mass. The natural history was one of restoration of varying degree in vertebral height. This could occur even though there had been almost complete collapse (vertebra plana) at the onset of the disease. Neurological complications were rare and the eventual outcome of all the patients did not appear to be affected by the type of treatment given.


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