Journal of Bone and Joint Surgery, 1969;51:704-712.
© 1969 by The Journal of Bone and Joint Surgery, Inc
Blastomycosis of Bone
TREATMENT WITH INTRAMEDULLARY AMPHOTERICIN-B
WILLIAM G. CUSHARD JR. M.D.1,
MOOSA KOHANIM M.D.1, and
LARRY R. LANTIS M.D.1
1 From the Departments of Medicine, of Orthopedic Surgery, and of Dermatology, the University of Pennsylvania and the Philadelphia Veterans Administration Hospital, Philadelphia
In a case of systemic North American blastomycosis, presenting as an apparently localized osteomyelitis, combined surgical and medical therapy with direct intramedullary and intravenous amphotericin-B effected apparent cure. The techniques and problems of diagnosis are reviewed.