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Journal of Bone and Joint Surgery, 1969;51:475-486.
© 1969 by The Journal of Bone and Joint Surgery, Inc

Immunologic Changes in Synovial Fluid Following Synovectomy of the Knee for Rheumatoid Arthritis

ANDREA CRACCHIOLO III M.D.1 and EUGENE V. BARNETT M.D.1

1 From the Departments of Surgery (Orthopedics) and of Medicine, University of California at Los Angeles School of Medicine, Los Angeles

Nineteen patients with classic or definite rheumatoid arthritis underwent synovectomy of twenty-two knees. These patients were primarily treated to improve their clinical status but they also served as experimental models for the study of immunologic factors in synovial fluid. Synovectomy resulted in frequent reductions of immunologic factors in synovial fluid but clinical improvement appears to be influenced by additional, possibly anatomical factors as well.


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