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Journal of Bone and Joint Surgery, 1968;50:1618-1628.
© 1968 by The Journal of Bone and Joint Surgery, Inc

Unusual Manifestations of Chordoma

A REPORT OF TWO CASES

JAMES E. FOX M.D.1, JOHN G. BATSAKIS M.D.1, and LUIS R. OWANO M.D.1

1 From the Department of Pathology, University of Michigan Medical Center, Ann Arbor, and The Swedish-American Hospital, Rockford, Illinois

Unusual behavior in two cases of chordoma are reported. The first is a sacral primary tumor with widespread metastases. Review of the literature indicates that

[See table in the PDF file]

well documented instances of metastases from these neoplasms are an uncommon occurrence; and that in the majority of cases the sacral area is the primary site. The second report is of a vertebral chordoma that underwent sarcomatous histological transformation three and one-half years after radiation therapy. This is apparently a previously unreported phenomenon.


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