This Article
Right arrow Full Text (PDF)
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowReprints and Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MILICIC, M.
Right arrow Articles by JOWSEY, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by MILICIC, M.
Right arrow Articles by JOWSEY, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Technorati  
What's this?
Journal of Bone and Joint Surgery, 1968;50:701-708.
© 1968 by The Journal of Bone and Joint Surgery, Inc

Effect of Fluoride on Disuse Osteoporosis in the Cat

MATKO MILICIC M.D.1 and JENIFER JOWSEY D. PHIL.1

1 From the Mayo Graduate School of Medicine and the Section of Surgical Research (Orthopedics), Mayo Clinic and Mayo Foundation, Rochester

Disuse osteoporosis induced in vertebrae of the tail distal to an area of resection of the coccygeal nerve and muscles, was studied in four adult cats fed fluoride from the age of six weeks on and in five adult control cats. Bone formation and bone resorption were quantitated by microradiography, and undecalcified bone sections were used to measure osteoid tissue. The development of disuse osteoporosis was not influenced by the presence of fluoride. The increase in bone density in patients with osteoporosis and other bone disease achieved with fluoride therapy may be the result of an increase in bone formation rather than a decrease in bone resorption.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Technorati Technorati    What's this?