This Article
Right arrow Full Text (PDF)
Right arrow Letters to the Editor: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Letters to the Editor are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowReprints and Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by HEIPLE, K. G.
Right arrow Articles by WATTLEWORTH, A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by HEIPLE, K. G.
Right arrow Articles by WATTLEWORTH, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Technorati  
What's this?
Journal of Bone and Joint Surgery, 1968;50:311-325.
© 1968 by The Journal of Bone and Joint Surgery, Inc

Osteogenic Induction by Osteosarcoma and Normal Bone in Mice

KINGSBURY G. HEIPLE M.D.1, CHARLES H. HERNDON M.D.1, SAMUEL W. CHASE PH.D.1, and ANTHONY WATTLEWORTH M.D.1

1 From the Division of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland

1. Osteogenic induction across a Millipore filter barrier by normal mouse calvarias and mouse osteosarcoma was demonstrated in mice.

2. The amount of external bone induction was considerably greater with two-week and eight-week-old mouse calvarias than with newborn calvarias, but the incidence of bone induction dropped sharply with eight-week calvarias.

3. The amount of external bone induction by the mouse osteosarcoma was from fifteen to seventy-five times greater than that by the normal bone.

4. External induction did not occur with any chamber in which bone was not growing or with any chamber containing rat calvaria or human osteosarcoma.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Technorati Technorati    What's this?