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Journal of Bone and Joint Surgery, 1968;50:113-122.
© 1968 by The Journal of Bone and Joint Surgery, Inc

Diastrophic Dwarfism

SAMUEL JOSEPH AMUSO M.D.1

1 From the Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh

Two case reports of diastrophic dwarfism are presented with discussion of its distinctive features.

The typical features of micromelic dwarfism, scoliosis, club feet, ear deformities, cleft palate, contracted interphalangeal joints, and hypermobile thumbs; and the roentgenographic characteristics of delayed, flattened, offset epiphyseal ossification centers; broad flared metaphyses; shortened, massive long bones; maldevelopment of the first metacarpal; and irregular ossification of the bones of the hand make this unique entity easily recognizable. Mentality and prognosis for life are good. However, the multiple deformities are often severe and highly resistant to corrective and reconstructive measures.


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