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Journal of Bone and Joint Surgery, 1966;48:92-99.
© 1966 by The Journal of Bone and Joint Surgery, Inc

Squamous-Cell Carcinoma of the Nail Bed in Epidermal Dysplasia

CRAWFORD J. CAMPBELL M.D.1 and THAMRONGRAT KEOKARN M.D.1

1 From the Division of Orthopedic Surgery, Albany Medical College of Union University Albany

A case of epidermal dysplasia is reported which squamous-cell carcinomata developed in the nail beds of two fingers.

Three fingers in this case were analyzed pathologically and compared with three fingers of a normal man of the same age. In epidermal dysplasia there was irregularity of all strata of the nail bed and a low-grade inflammatory reaction in the corium. It is our impression that the irregularity of growth in epidermal dysplasia could in itself be a precursor to the development of squamous-cell carcinoma.


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