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Journal of Bone and Joint Surgery, 1965;47:762-772.
© 1965 by The Journal of Bone and Joint Surgery, Inc

Malignant Hemangioendothelioma of Bone

REPORT OF TWO CASES AND REVIEW OF THE LITERATURE

WARNER D. BUNDENS JR. M.D.1 and CARL T. BRIGHTON 2

1 Temple University School of Medicine, Philadelphia, Pennsylvania
2 Orthopaedic Service, United States Naval Hospital, Great Lakes, Illinois

1. Two cases of malignant hemangioendothelioma of bone are presented, and the world's literature is reviewed. In all, there are thirty-four adequately documented cases of this rare primary bone tumor.

2. The clinical and roentgenographic features are non-specific.

3. The histological characteristic of this lesion is an overproduction of atypical endothelial cells that frequently form anastomosing vascular clefts.

4. Prognosis and treatment are discussed.


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