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Journal of Bone and Joint Surgery, 1962;44:464-468.
© 1962 by The Journal of Bone and Joint Surgery, Inc

Sulphate Metabolism in Cartilage

III. The Effect of Various Adjuvants on Sulphate Exchange in Cartilage Slices

O. Donald Chrisman M.D.1 and Wayne O. Southwick M.D.1

1 Department of Orthopaedic Surgery, Yale University School of Medicine, New Haven

Joint fluid from patients with severe degenerative arthritis and loose-body formation was shown to arrest the degradation of chondroitin sulphate usually seen in cartilage slices during incubation. Only hyaluronic acid of the several adjuvants tested had a similar effect.


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