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Journal of Bone and Joint Surgery, 1960;42:609-616.
© 1960 by The Journal of Bone and Joint Surgery, Inc

Simple Bone Cysts

Studies of Cyst Fluid in Six Cases with a Theory of Pathogenesis

Jonathan Cohen M.D.1

1 Departments of Orthopaedic Surgery and Pathology and Division of Laboratories and Research, Children's Medical Center, Boston

Cyst fluid of six simple cysts of bone was aspirated and determinations of electrolytes and protein content made. In four of the cysts the fluid resembled plasma. In two others it resembled blood. A theory of etiology of simple cysts is suggested in which the principal etiological factor is blockage of the drainage of interstitial fluid in a rapidly growing and rapidly remodeling area of cancellous bone.


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