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Journal of Bone and Joint Surgery, 1960;42:414-429.
© 1960 by The Journal of Bone and Joint Surgery, Inc

Pyogenic Osteomyelitis and Arthritis of the Spine Treated with Combinations of Antibiotics and Gamma Globulin

A Preliminary Report

Burton A. Waisbren M.D.1

1 Infectious Disease Control Unit of the Department of Medicine of the Milwaukee County General Hospital and the Marquette University School of Medicine

Eight cases of pyogenic osteomyelitis of the spine are presented in which a satisfactory clinical response was obtained with combinations of antibiotics with human gamma globulin. It is suggested that certain patients with this disease who are not responding to conventional methods of therapy may benefit from the administration of combinations of antibiotics and gamma globulin, and that prolonged maintenance therapy with antibiotics may be necessary to prevent recurrence.


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