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Journal of Bone and Joint Surgery, 1959;41:1521-1525.
© 1959 by The Journal of Bone and Joint Surgery, Inc

Bone-Marrow Eosinophilia with Solitary Eosinophilic Granuloma of Bone

A Report of Two Cases

Ralph C. Marcove M.D.1

1 Department of Pathology, Hospital for Joint Diseases, New York

An elevation of the eosinophils in the differential count of the bone marrow was found in the two patients presented in this paper (and in the three others mentioned). This was in sharp contrast to the peripheral-blood studies which revealed no remarkable deviation from the normal counts expected.

Bone-marrow findings as described in this paper may be helpful in leading one toward the diagnosis of eosinophilic granuloma.

A new method of counting eosinophils in the bone marrow is described and can be used to check counts done by smear or clotted and fixed marrow sections.


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